Missouri Marijuana License
Missouri allows adult-use and medical cannabis under its state constitution. The Division of Cannabis Regulation licenses a capped number of comprehensive and microbusiness facilities, and new applications are currently closed.
Overview
Missouri voters legalized medical marijuana in 2018 (Amendment 2) and adult-use cannabis in 2022 (Amendment 3). The Division of Cannabis Regulation, part of the Department of Health and Senior Services, licenses facilities.
License numbers are capped by the constitution. Existing medical facilities converted to comprehensive licenses, and new microbusiness licenses, reserved for disadvantaged applicants, are awarded by lottery. Applications for comprehensive cultivation, manufacturing, testing and dispensary licenses are currently closed.
License Types
- Comprehensive Cultivation
- Comprehensive Manufacturing
- Comprehensive Dispensary
- Microbusiness Dispensary and Microbusiness Wholesale
- Certifications: testing laboratory, transportation, seed-to-sale and offsite warehouse
Key Requirements
- Majority ownership by Missouri residents (one-year residency) where required
- Microbusiness applicants must meet eligibility criteria, such as low income, veteran status, disability or prior cannabis offenses
- Compliant location meeting local zoning and buffer rules
- Security, inventory tracking (Metrc) and background checks
Fees
- Application fees (July 2026–June 2027): Comprehensive Cultivation $5,139; Comprehensive Dispensary or Manufacturing $3,083.40; Microbusiness Dispensary or Wholesale $1,637; certifications $2,892.03 each
- Annual fees: Comprehensive Cultivation $28,920.33; Comprehensive Dispensary or Manufacturing $11,568.13; Microbusiness $1,637
Fees are adjusted annually for inflation.
Application Process
- Watch the DCR website for an application window or microbusiness lottery.
- Confirm eligibility, especially for microbusiness licenses.
- Submit the application and fee during the window.
- Eligible applicants are selected by lottery where applications exceed available licenses.
- Pass a commencement inspection before operating.
Regulations
- Adults 21+ may possess up to 3 ounces and grow up to 6 flowering plants with a personal cultivation card
- License numbers are capped and tied to population
- Local governments can regulate time, place and manner
Medical Marijuana Card
Who qualifies
- Missouri resident with a qualifying condition, including cancer, epilepsy, glaucoma, chronic pain, PTSD, psychiatric disorders and any condition a physician certifies as debilitating
- Certification from a physician or nurse practitioner
How to apply
- Get a certification from a physician or nurse practitioner.
- Apply online with the DCR and upload your certification.
- Pay the ID card fee and buy at any dispensary.
More guides for this state
Licensing professionals in this state
View all →Are you a cannabis attorney or licensing consultant serving this state? Featured placement here is available.
Feature your firm →Featured listings may be paid placements. MarijuanaLicense.com doesn't endorse any professional.
Get matched with a licensing pro in your state
Tell us what you're planning. We'll connect you with up to three cannabis attorneys or licensing consultants who work in this state.
MarijuanaLicense.com may receive a referral fee from professionals we connect you with. This never affects the cost to you. We're an independent resource, not a government agency.
MarijuanaLicense.com is an independent informational resource and is not affiliated with any state agency. This page is for general information only and is not legal advice. Fees, rules and application windows change; confirm with the official regulator before applying.
Written and maintained by the MarijuanaLicense.com Editorial Team. Learn how we research and verify our guides, or report a correction.
